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The Independent UK
The Independent UK
National
Nick Forbes

HISTORICAL FACTS: Breakthrough as medics develop single dose malaria drug - The Untold Story

  • Researchers at the University of Dundee have discovered a novel antimalarial compound named cabamiquine, offering a promising step forward in global efforts to combat malaria.
  • The drug-like molecule can be administered in a single dose, which could significantly simplify treatment and prevention regimens in areas where healthcare access is challenging.
  • Early-stage trial results published in The Lancet Infectious Diseases showed that cabamiquine combined with existing drug pyronaridine was safe and effective in adults and teenagers.
  • Global data from 2024 estimates there were 282 million malaria cases and 610,000 deaths worldwide, with figures rising partly due to growing resistance to existing treatments.
  • Medicines for Malaria Venture plans to progress the combined therapy into larger clinical trials, including testing among paediatric patients.

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