The Indianapolis Colts (4-9-1) remain home underdogs against the Los Angeles Chargers (8-6) for the Week 16 matchup at Lucas Oil Stadium.
Not much really changed on the betting front since the opening odds were released for this Week 16 prime-time matchup.
According to Tipico Sportsbook, here are the updated odds for the game:
| Spread | Moneyline | Total Points | |
| Los Angeles Chargers (8-6) | -4 | -210 | O 45.5 -110 |
| Indianapolis Colts (4-9-1) | +4 | +180 | U 45.5 -110 |
Over the week, the spread moved a half-point in the favor of the Colts while the moneyline moved slightly in favor of the Chargers. The over/under total moved down one full point.
The Colts have been officially eliminated from playoff contention so they’re playing for their pride while the Chargers are competing for a playoff spot as a wild-card team.
This will be the Colts’ final prime-time game of the season as they begin to shift their focus on a potential top-five draft pick.
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