Sir Keir Starmer appeared to criticise Donald Trump as he said he was “fed up” with how the actions of the US President could impact the cost of living in Britain.
He also appeared to compare the US-Israeli war with Iran to Vladimir Putin’s decision to invade Ukraine.
The Prime Minister’s comments gave further evidence of his strained relationship with the US president.
It comes after weeks of repeated criticism of the Sir Keir by Trump over his refusal to join the offensive in the Iran war.
The Prime Minister spoke put as he said he was unhappy with the impact of the Iran war on the domestic cost of living durin ghis trip to the Gulf.
Sir Keir told ITV’s Robert Peston: “I’m fed up with the fact that families across the country see their bills go up and down on energy, businesses’ bills go up and down on energy because of the actions of Putin or Trump across the world.”
He also split with the US president over Israel’s attacks on Lebanon, saying the strikes “shouldn’t be happening”.
“That should stop – that’s my strong view – and therefore, the question isn’t a technical one of whether it’s a breach of the agreement or not,” Sir Keir said during his visit to the Gulf.
“We haven’t all got access to all the details of the ceasefire,” Sir Keir said, but added: “Let me be really clear about it – they’re wrong.”
Separately, writing in the Guardian, the Prime Minister said the UK must become more resilient to deal with a "volatile and dangerous" world where "shocks" like the conflict in Iran are frequent.
Writing in The Guardian, Sir Keir Starmer said he was "thinking about the long-term, and remaking this country" so that people "are not at the mercy of events abroad".
In his article for the Guardian, Sir Keir said Britain had been "buffeted by crises for nearly two decades", citing the 2008 financial crash, Brexit and Covid.
"The response from Westminster has always been the same - manage the crisis, find a sticking plaster and then desperately try to reassert the status quo."
He promised that "this time, it will be different" and that the conflict in Iran "must now become a line in the sand".
He argued that government policies such as investing in renewable energy, strengthening workers' rights and removing the two-child benefit cap would help prepare the country for increased global instability.
"Because resilience is what gives us control. Without it, we are constantly pushed off course by events beyond our borders."
Sir Keir has spoken to Trump about the need for a "practical plan" to get shipping going through the Strait of Hormuz in the wake of the Middle East ceasefire.
The Prime Minister has been visiting allies in the Gulf for talks on how to support the pause in fighting and secure a permanent reopening of the key shipping strait.
He is set to head back to the UK on Friday after visiting Qatar, Bahrain, Saudi Arabia and the United Arab Emirates.
On Thursday a Downing Street spokesperson said: "The Prime Minister spoke to President Trump from Qatar this evening.
"The Prime Minister set out his discussions with Gulf leaders and military planners in the region on the need to restore freedom of navigation in the Strait of Hormuz, as well as the UK's efforts to convene partners to agree a viable plan.
"They agreed that now there is a ceasefire in place and agreement to open the strait, we are at the next stage of finding a resolution.
"The leaders discussed the need for a practical plan to get shipping moving again as quickly as possible."
Sir Keir earlier said the ships passing through the Strait of Hormuz must have "toll-free navigation" as part of the ceasefire amid reports Iran wants to charge for passage.
Asked whether he viewed the critical strait as now being open, he said: "There are a lot of things being said - they need to be tested" and that the UK's position is that "open" means "open for safe navigation".
"That means toll-free navigation and vessels can get through," he told ITV's Talking Politics Podcast.
Speaking in London, the Foreign Secretary also called for toll-free travel through the Strait, warning that trading routes from Qatar, UAE, Bahrain, Kuwait, Iraq, Saudi Arabia and Oman were "all hijacked by Iran so that they can hold the global economy hostage".
Yvette Cooper said: "The fundamental freedoms of the seas must not be unilaterally withdrawn or sold off to individual bidders and nor can there be any place for tolls on an international waterway."
The US president later posted on his Truth Social platform: "There are reports that Iran is charging fees to tankers going through the Hormuz Strait - They better not be and, if they are, they better stop now! President DONALD J. TRUMP."
He added in a separate post: "Iran is doing a very poor job, dishonorable some would say, of allowing Oil to go through the Strait of Hormuz. That is not the agreement we have!"
