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UNCOVERED: Oncology | History Defined

Ifosfamide Is Scarce at 94 Percent of Surveyed Cancer Centers, and Every Responding Center Reports a Drug Shortage

Every cancer center in a new NCCN survey reports at least one drug shortage, led by ifosfamide. What patients in treatment should ask now.

Medical Daily

Strategic Decision-Making in Complex Clinical Development Programs

Clinical development decisions made before a study begins can have consequences throughout the entire research program.

inkl

5 Self-Examination Techniques That Catch Cancer and Skin Disease Early in Just Ten Minutes a Month

Why Your Hands Are the First Line of ScreeningA 2022 study published in The Lancet Oncology found that in low- and middle-income countries, a category India still partially occupies for cancer infrastructure, over 60 percent of breast cancer cases present at stage three or four. The gap between early and…

Times Life

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A Blood Test, Not a Scan, Now Triggers This Breast Cancer Treatment Switch Under Accelerated Approval

FDA granted accelerated approval to camizestrant, the first cancer therapy that starts when a blood test finds resistance before scans show progression.

Medical Daily

Ohio Opens a Cancer Navigator Office After a West Chester Family Spent His Final Weeks Fighting Paperwork

Ohio created a Pediatric Complex Care Navigation Program after Jayden Zurlinden died at 20. It is open to families at any income level.

Medical Daily

A 76 Year Old with Stage 4 Cancer Has Missed Two Oncology Appointments Since ICE Detained Him

Loreto Javar, 76, has stage 4 prostate cancer and missed two oncology appointments while in ICE detention. Why interrupted cancer care carries real risk.

Medical Daily

Priscilla Chan's grandfather died of cancer when she was in sixth grade; she found a cancer textbook and taught herself why he died

Priscilla Chan was in sixth grade when the death of her grandfather from cancer changed the direction of her life. One morning, he dropped her off at her sixth-grade classroom, but by the time she returned home, he had died. Chan was left trying to understand how someone who had…

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Two Drugmakers Have Paused Autoimmune CAR T Cell Trials After Three Deaths from a Severe Immune Reaction

Novartis paused eight autoimmune CAR T trials after three severe immune reactions, and Bristol Myers Squibb paused enrollment in its program.

Medical Daily

Oncologists Just Got a Three Tier Rationing Playbook for a Chemotherapy Drug with No Substitute

ASCO has directed cancer practices to a federal conservation framework as ifosfamide, a chemotherapy with no direct substitute, runs critically low.

Medical Daily

Why NRIs Are Returning to India for Medical Treatment, and What It Costs Them Beyond Money

The Appointment You Didn't Expect to MakeThe cardiologist's waiting room in Chennai or Medanta or Kokilaben looks nothing like the one you sat in abroad. It is louder, more crowded, occasionally chaotic. A man argues with a billing clerk two windows down. A woman feeds her mother a biscuit from…

Times Life

Cancer Practices Report Only Weeks of Ifosfamide on Hand as Oncologists Warn No Substitute Drug Exists

ASCO warns some oncology practices have under a few weeks of ifosfamide left, with no direct substitute for the chemotherapy drug.

Medical Daily

Two New Drug Combinations Win Approval as the First Treatment for an Aggressive Stomach and Esophageal Cancer

The FDA approved two Ziihera regimens as first-line treatment for HER2-positive advanced gastroesophageal cancer, plus two companion diagnostic tests.

Medical Daily

The $1.24 Billion Reason Why Kura Oncology Stock Is Up Today

Kura Oncology stock rallies as the CEO revealed another $1.24 million purchase of company shares. Wall Street continues to see massive further upside in KURA shares.

Barchart

Patients and Researchers Push Back on Cancer Drug Doses That May Be Higher Than Treatment Requires

A KFF Health News investigation finds cancer drugs are often approved at doses higher than needed, leaving patients with avoidable side effects.

Medical Daily

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The Economic Times

Lord's Mark Industries outlines strategic expansion across global healthcare, advanced diagnostics & oncology; targets ₹1,550 Crore revenue in FY2027

In a strategic shift, Lord's Mark Industries is set to launch an extensive healthcare expansion alongside a business demerger. This initiative will prioritize advancements in diagnostics, oncology, and cutting-edge medical devices, bringing CAR-T cell therapy and specialized oncology hospitals to a wider Indian demographic. The company's international vision includes launching…

Medical Daily

FDA Accepts Review of a Pancreatic Cancer Pill Already Reaching Patients Through an Expanded Access Program

The FDA accepted the daraxonrasib application in July, and more than 2,000 patients are already receiving the drug without approval.

Medical Daily

FDA Clears a New Class of Myeloma Drug for Patients Whose Cancer Returned After Earlier Treatment

The FDA granted accelerated approval to iberdomide, the first CELMoD for relapsed multiple myeloma, usable as early as first relapse.

Medical Daily

Cancer Patients Now Wait About 10 Days Longer to Start Treatment Than They Did a Decade Ago

A JAMA Surgery study of more than 2.7 million patients found that wait times from cancer diagnosis to first treatment rose across all six cancers studied.

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Barchart

Relay Therapeutics Stock Is Up Nearly 500% Over the Past Year

Relay Therapeutics (RLAY) is a clinical-stage precision medicines company focused on targeted oncology, with a $4.4 billion market cap. RLAY has surged 486% over the past year. Shares are trading near a new 3-year high. Technical momentum is strong, but fundamentals show that revenue is expected to decrease by more...

Medical Daily

FDA Approves Replimune's Tudriqev for Advanced Melanoma After Two Previous Rejections

FDA granted accelerated approval to Tudriqev with nivolumab for advanced melanoma after two rejections. Who qualifies and what evidence is still owed.

Medical Daily

Large Trial Finds High-Dose Vitamin D Did Not Slow Metastatic Colorectal Cancer

A phase 3 trial in 455 patients found high-dose vitamin D3 did not improve survival in metastatic colorectal cancer, reversing an earlier signal.

Medical Daily

Cleveland Clinic Breaks Ground on $322 Million Avon Expansion Adding Beds, Operating Rooms and Cancer Services

Cleveland Clinic began a $322 million expansion of its Avon campus, adding beds, ORs, imaging and cancer capacity for Lorain County through 2029.

Times Life

6 Common Stomach Cancer Risk Factors Found in Indian Kitchens and Daily Habits

The Salt in Your AchaarSalt is the oldest preservative in the Indian pantry, and achaar, papad, and salted dried fish are eaten across every region without a second thought. The problem is volume. A 2019 review published in the International Journal of Cancer found that high dietary salt intake is…

Times Life

Cervical Cancer Is Almost Entirely Preventable. So Why Does It Still Kill So Many Women in India

Numbers That Should Not ExistEvery eight minutes, an Indian woman dies of cervical cancer. That figure comes from ICMR data published in its National Cancer Registry Programme report, and it has not moved in the direction it should. India records roughly 1.25 lakh new cervical cancer cases annually and accounts…

Medical Daily

FDA Tells Cancer Trial Sponsors to Stop Copying Eligibility Rules That Lack Scientific Support

FDA finalized three guidances telling cancer trial sponsors to justify lab value, performance status, and washout period exclusions rather than copying them.

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