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LiveScience

Jennifer Zieba

INSANE: Could crispr cure hiv someday | Rare Historical Photos

HIV Live Science Clinical Trial

Close-up of a gloved hand using tweezers to pull genetic material from a suspended DNA molecule.

In an ongoing clinical trial, researchers are testing whether just one dose of a new gene therapy that might effectively cure human immunodeficiency virus (HIV) infections is safe in humans.

The therapy, named EBT-101, involves using CRISPR-Cas9 gene editing to treat HIV. This potential treatment strategy has been studied in animal models since the development of CRISPR-Cas9 in 2012. However, this is the first time such a gene-editing treatment for HIV has been tried in humans. The latest data from the trial suggest that EBT-101 is safe at the doses tested, but we don't yet know if it cures HIV.

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