
As cannabis becomes legal in more regions, it's important for the public to understand the risk of overdose in order to prevent harm, just like we do with other drugs like alcohol and prescription medications. People use marijuana for good reasons. There are medicinal benefits, but it also just feels good. Ingesting THC either through smoking, vaporizing or edibles can make people feel euphoric, relaxed, sleepy, giggly and otherwise intoxicated.
According to Allen, these antagonists are so effective that someone could take one and ingest as much cannabis as they want and they couldn't get high.