Postpartum depression is a significant public health issue, costing the UK economy around £74,000 for a single case according to 2018 research. Postpartum depression, among other symptoms, typically involves the mother feeling ‘disconnected’ — from herself, her infant and her support system. Current treatment for postpartum depression is largely based on that used in general adult depression. While these treatment options help some women with postpartum depression, they don’t work for all.
A recent review of the therapeutic use of psychedelics such as lysergic acid diethylamide (LSD) and psilocybin (the active agent in ‘magic mushrooms’) suggests they may be useful in treating postpartum depression by improving the mother-infant relationship. Clinical trials have shown that psilocybin can be safe when used in therapeutic environments alongside appropriate psychedelic therapist support. Psilocybin also shows promise in treating depression in adults, but larger trials are needed before it can be approved.
The symptoms of postpartum depression can include low mood, an inability to feel pleasure, insomnia, poor concentration, and feelings of inadequacy or guilt. One in five women with postpartum depression think about self-harm, and some have thoughts of harming their infant. In addition to these symptoms, or perhaps because of them, most women with postpartum depression lose confidence in their abilities as a mother.