
Metformin, a widely used diabetes medication, may lower blood sugar through a previously unrecognised pathway in the brain, according to new research. The drug is commonly prescribed to people with type 2 diabetes, a condition in which the body cannot properly regulate blood sugar levels.
Scientists said the findings suggest the drug does not act only in the liver and gut, as previously understood. Researchers at Baylor College of Medicine said the mechanism involves a protein known as Rap1 in a region of the brain called the hypothalamus.