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UNCOVERED: 10 | History Defined

The Zika genome and insights in the era of emerging outbreaks

Zika and dengue viruses infect up to 400 million people annually. Genomic studies of Zika have revealed its spread, diagnosis, epidemiology, and pathogenesis. Recent studies have found that viral load and DENV infections influence microcephaly following Zika infections. Zika and DENV interactions can also increase the severity of dengue disease.

The Hindu

NIAB scientists design a vaccine candidate against LSD virus

The Hindu

How bat genomes provide insights into immunity and cancer

The COVID-19 pandemic cast a bright spotlight on the habits of bats. Over the years, researchers have unearthed significant insights by sequencing the genomes of many bat species.

The Hindu

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Avian influenza viruses undergo major evolutionary changes

H5N1 virus activity has intensified globally since 2021, posing risk to humans. A study in Nature reveals a shift in the epicentre of these viruses from Asia to Africa and Europe. Analysis of 10,000 viral genomes and epidemiological data shows new strains have evolved through genetic reassortment. Findings suggest persistence…

The Hindu

How Neanderthal DNA got ‘diluted’ among Europeans finally found

‘Genomes of farmers from Anatolia diluted Neanderthal DNA a little more’

The Independent UK

Wild plants may edit their genomes in the same way we make GM crops – and it could be crucial to evolution

Genetically modified (GM) crops may be controversial, but similar processes happen naturally with wild plants. However, scientists have long been puzzled about how these processes happen. Our recent study may help researchers solve the mystery.

The Conversation

There are 750 unidentified human remains in Australia. Could your DNA help solve one of these cold cases?

Yesterday it was announced the Australian Federal Police (AFP) National DNA Program for Unidentified and Missing Persons used advanced DNA technology to assist South Australia Police resolve a 40-year-old missing persons case.

The Conversation

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NIAB scientists decode genome of indigenous cattle

The Hindu

Why BSL-3 lab for Nipah confirmation is unnecessary

Kerala has now been allowed to use Truenat for Nipah testing, but only in BSL-2 facilities. ICMR insists on BSL-3 for confirmation, despite Truenat inactivating the virus. NIV had validated the lysis buffer and transport medium to be highly effective in inactivating the virus.

The Hindu

Genomic clues suggest humans’ ancestors nearly went extinct 9L years ago

Genome sequencing has enabled researchers to uncover population bottlenecks, founder events, and the age of genetic diseases in the history of human evolution and migration. Ancient DNA recently revealed a super-bottleneck in human evolution 900,000 years ago, which could have shaped humanity in ways we don't yet know. Genomic analysis…

The Hindu

Belgium firm Eurofins opens bio-pharma services campus at Genome Valley

The Hindu

BSV breaks ground for ₹200 crore bio-pharmaceutical plant at Genome Valley

The Hindu

Study finds how bats evolved to avoid cancer

A new research published by Oxford University Press in Genome Biology and Evolution suggests that rapid evolution in bats may explain the animals' unique capacity to host and survive infections as well as avoid cancer. Read further on Dynamite News:

Dynamite News

Spanish pharma MNC’s facility in Genome Valley opened

Insud Pharma inaugurated its Oligonucleotides centre in Genome Valley, India, approved by U.S. FDA, Spanish Health Agency, and Drugs Controller General of India. It will produce a novel antisense Oligonucleotide for the treatment of Spinal Muscular Atrophy (SMA) and export products to various markets. Chemo India Formulation, a wholly-owned subsidiary,…

The Hindu

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The Hindu

Syngene plans to invest ₹788 cr. to expand operations in Hyderabad’s Genome Valley

Syngene to invest up to ₹788 cr in Genome Valley, Hyderabad. Expansion to create 1,000 jobs in science over 5 yrs. Inaugurated PROTAC lab & Central Compound Management facility. Ease of doing business & living in Telangana praised by Syngene's non-executive chairperson Kiran Mazumdar Shaw.

The Hindu

Buzzing breakthrough: genetic engineering gives mosquito control an upgrade

Mosquitoes have plagued humans for centuries, transmitting deadly diseases. To combat this, we now have access to the whole genome sequences of multiple mosquito species, allowing us to genetically manipulate them. Gene-drive technology is one such approach, which has been used in outdoor trials in India, Brazil, and Panama, showing…

The Conversation

How gene mapping almost all remaining kākāpō will help NZ’s rare night parrot survive

The genetic mapping of almost the entire kākāpō population has shed new light on specific traits that will help conservation biologists in their efforts to save the critically endangered flightless night parrots.

The Hindu

Somatic genetic variants: A genomic revolution hiding inside our cells

Scientists have known of somatic variants and their role in diseases for many years now, but there has been an explosion in the amount of data and knowledge only recently. This was due to our ability to sequence the genetic material in individual cells. Specifically, using advanced microfluidics and high-throughput…

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The Independent UK

A broad genetic test saved one newborn's life. Research suggests it could help millions of others

A recent study showed that tests for sick newborns that look at their full genetic blueprints are nearly twice as good at finding genetic problems as narrower, more commonly used tests

The Conversation

New research reveals that Ötzi the iceman was bald and probably from a farming family – what else can DNA uncover?

In 1991, hikers came across a body that was partially contained in ice high up in the Alpine province of South Tyrol, Italy. Initially thought to be from a recent death, the body was later discovered to be 5,300 years old – from a time known as the Copper Age.

The Conversation

Scientists find the last remnants of the human genome that were missing in the Y chromosome

More than 20 years ago, the human genome was first sequenced. While the first version was full of “holes” representing missing DNA sequences, the genome has been gradually improved in successive rounds. Each has increased the quality of the genome and, in so doing, resolved most of the blank spaces…

LiveScience

The human Y chromosome has finally been fully sequenced, 20 years after the 1st draft

One of the smallest chromosomes in humans, the male sex chromosome is the final one to be fully sequenced.

The Conversation

New research into genetic mutations may pave the way for more effective gene therapies

Consider a living cell, which can have thousands of genes. Now think of these genes as dials that can be tweaked to change how the cell grows in a given environment. Tweaking a gene can either increase or decrease growth, and this is made more complex considering these dials are…

The Hindu

‘India must ramp up testing and maintain close watch on new global variants of COVID-19’

India must monitor Influenza-like Illness, Severe Acute Respiratory Infections cases, ramp up Whole Genome Sequencing, says P.K. Mishra. India's COVID-19 situation stable, global cases up; Health Ministry provides overview of variants, India's weekly test positivity rate <0.2%.

Zenger

New Research Reveals Ötzi The Iceman’s Real Appearance

“The mummy itself, however, is dark and has no hair.”

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