HISTORICAL FACTS: Sickle cell disease - The Untold Story

Only 3% of US sickle cell patients receive red blood cell exchange for disease, researchers find

Various factors block sufferers of disease from receiving treatment that is effective and has widespread availability

The Guardian - US · Sep 27

A Sickle Cell Headache That Ends in Brain Surgery Has Been Documented Fewer Than 80 Times

Spontaneous bleeding inside the skull during a sickle cell crisis has fewer than 80 documented cases, and dead skull bone shifts the odds.

Medical Daily · Sep 2

7 Things Every Indian With Sickle Cell Trait Should Know About Their Health

You are a carrier, not a patient, but the distinction has limitsSickle cell trait means you inherited one copy of the HbS gene and one normal copy. Your body produces both haemoglobin A and haemoglobin S. Under ordinary conditions, you will not have a sickle cell crisis. The Indian Council…

Times Life · Aug 31

FDA drug approval affects healthcare around the world, but political shortcuts could hurt the agency’s international reputation

At the beginning of July 2026, the U.S. Food and Drug Administration approved the first gene therapy for young children with sickle cell disease.

The Conversation · Jul 15

Medicaid Will Cover Sickle Cell Gene Therapy, but Only When It Actually Works for the Patient

CMS's CGT Access Model now covers Casgevy and Lyfgenia for sickle cell through 33 state Medicaid programs under outcomes-based contracts. Here's what patients need to know.

Medical Daily · Jul 8

A 23-Year-Old Louisiana Man Became the First Person in the Gulf South to Be Functionally Cured of Sickle Cell Disease

Daniel Cressy, 23, is the first person in the Gulf South functionally cured of sickle cell disease using Casgevy CRISPR gene therapy at Manning Family Children's Hospital in New Orleans.

Medical Daily · Jul 6

Louisiana man becomes first in region functionally cured of sickle cell disease

Daniel Cressy, 23, says path leading to completion of curative gene therapy is his ‘greatest blessing’

The Guardian - US · Jun 24

Aflac general counsel: Georgia lawmakers took a crucial step forward on sickle cell disease – but there's more work to be done

A new Georgia law requires Medicaid to keep pace with sickle cell treatments. With World Sickle Cell Day on June 19, here's why every state needs to act now.

Fortune · Jun 19

India can eradicate sickle cell disease before 2047 through collective efforts: President Murmu

President Droupadi Murmu believes India will eliminate sickle cell disease before the 2047 target. She stressed the need for increased awareness, particularly within tribal communities. The President stated that collective efforts from all states will achieve this national goal. She highlighted that treatment is possible and the disease can be…

The Economic Times · Jun 19

CRISPR Gene Editing Achieves a Functional Cure for Sickle Cell Disease in 96 Percent of Patients — RUBY Trial Results in the New England Journal of Medicine Are Historic

The RUBY Trial (NEJM, April 2026): CRISPR-Cas12a gene editing therapy reni-cel (renizgamglogene autogedtemcel) achieved a functional cure in 27 of 28 (96%) severe sickle cell disease patients, with no painful crises for up to two years after treatment. Led by Dr. Rabi Hanna at Cleveland Clinic.

Medical Daily · Jun 13