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HISTORICAL FACTS: 9 | History Defined

Study reveals new genes can arise from nothing

The human genome contains ca. 20,000 genes that are used for the construction of proteins. Actions of these classical genes are coordinated by thousands of regulatory genes, the smallest of which encode microRNA molecules that are 22 base pairs in length. Read further on Dynamite News:

Dynamite News

The unusual cabbage mutation that could boost crop yield | Explained

Deleting a single base-pair from the genome of plants like cabbage, cauliflower, broccoli, tomato, and rice can make them male-sterile, leading to an abundant harvest of hybrid seeds. This is due to a process called heterosis, which is enabled by the fine balance of the Ms-cd1 protein's levels. The mutation's…

The Hindu

The transformative benefits of population-level genome sequencing | Explained

A revolutionary shift in genomics tech has enabled population-scale sequencing, leading to unprecedented insights into humans’ genetic diversity. UK's 100K Genome project, deCODE's Icelandic effort, Diversity Human Genome Initiative, AllofUS, 1+ Million Genomes, 3M African Genomes, Emirati genome programme, GenomeAsia, IndiGen, and GenomeIndia - all aim to sequence lakhs of…

The Hindu

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UK Biobank releases world’s largest set of whole genome sequencing data

Among other things, the data could enable researchers to look at a person’s individual risk of common disease.

The Independent UK

MicroRNA is the master regulator of the genome − researchers are learning how to treat disease by harnessing the way it controls genes

The Earth formed 4.5 billion years ago, and life less than a billion years after that. Although life as we know it is dependent on four major macromolecules – DNA, RNA, proteins and lipids – only one is thought to have been present at the beginning of life: RNA.

The Conversation

The unusual ‘mutations’ that protect humans from viruses | Explained

Paramutations protect humans against viruses and are triggered by piRNA clusters, which are 3% of the fruit fly genome. Paramutations involve a small chemical modification of a chromosomal protein, flipping a nearby gene into a silenced state. William Bateson and Caroline Pellew discovered the first paramutation in the culinary pea…

The Hindu

A Thanksgiving hero: the cranberry

"Cranberries' close association with Thanksgiving was simply a practical matter at first"

Salon

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Cranberries can bounce, float and pollinate themselves: The saucy science of a Thanksgiving classic

Cranberries are a staple in U.S. households at Thanksgiving – but how did this bog dweller end up on holiday tables?

The Conversation

Scientists create baker’s yeast with more than 50% synthetic DNA

The overarching aim was to build a yeast that can teach us new biology, researchers said.

The Independent UK

The Zika genome and insights in the era of emerging outbreaks

Zika and dengue viruses infect up to 400 million people annually. Genomic studies of Zika have revealed its spread, diagnosis, epidemiology, and pathogenesis. Recent studies have found that viral load and DENV infections influence microcephaly following Zika infections. Zika and DENV interactions can also increase the severity of dengue disease.

The Hindu

NIAB scientists design a vaccine candidate against LSD virus

The Hindu

How bat genomes provide insights into immunity and cancer

The COVID-19 pandemic cast a bright spotlight on the habits of bats. Over the years, researchers have unearthed significant insights by sequencing the genomes of many bat species.

The Hindu

Avian influenza viruses undergo major evolutionary changes

H5N1 virus activity has intensified globally since 2021, posing risk to humans. A study in Nature reveals a shift in the epicentre of these viruses from Asia to Africa and Europe. Analysis of 10,000 viral genomes and epidemiological data shows new strains have evolved through genetic reassortment. Findings suggest persistence…

The Hindu

How Neanderthal DNA got ‘diluted’ among Europeans finally found

‘Genomes of farmers from Anatolia diluted Neanderthal DNA a little more’

The Independent UK

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The Conversation

Wild plants may edit their genomes in the same way we make GM crops – and it could be crucial to evolution

Genetically modified (GM) crops may be controversial, but similar processes happen naturally with wild plants. However, scientists have long been puzzled about how these processes happen. Our recent study may help researchers solve the mystery.

The Conversation

There are 750 unidentified human remains in Australia. Could your DNA help solve one of these cold cases?

Yesterday it was announced the Australian Federal Police (AFP) National DNA Program for Unidentified and Missing Persons used advanced DNA technology to assist South Australia Police resolve a 40-year-old missing persons case.

The Hindu

NIAB scientists decode genome of indigenous cattle

The Hindu

Why BSL-3 lab for Nipah confirmation is unnecessary

Kerala has now been allowed to use Truenat for Nipah testing, but only in BSL-2 facilities. ICMR insists on BSL-3 for confirmation, despite Truenat inactivating the virus. NIV had validated the lysis buffer and transport medium to be highly effective in inactivating the virus.

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The Hindu

Genomic clues suggest humans’ ancestors nearly went extinct 9L years ago

Genome sequencing has enabled researchers to uncover population bottlenecks, founder events, and the age of genetic diseases in the history of human evolution and migration. Ancient DNA recently revealed a super-bottleneck in human evolution 900,000 years ago, which could have shaped humanity in ways we don't yet know. Genomic analysis…

The Hindu

Belgium firm Eurofins opens bio-pharma services campus at Genome Valley

The Hindu

BSV breaks ground for ₹200 crore bio-pharmaceutical plant at Genome Valley

Dynamite News

Study finds how bats evolved to avoid cancer

A new research published by Oxford University Press in Genome Biology and Evolution suggests that rapid evolution in bats may explain the animals' unique capacity to host and survive infections as well as avoid cancer. Read further on Dynamite News:

The Hindu

Spanish pharma MNC’s facility in Genome Valley opened

Insud Pharma inaugurated its Oligonucleotides centre in Genome Valley, India, approved by U.S. FDA, Spanish Health Agency, and Drugs Controller General of India. It will produce a novel antisense Oligonucleotide for the treatment of Spinal Muscular Atrophy (SMA) and export products to various markets. Chemo India Formulation, a wholly-owned subsidiary,…

The Hindu

Syngene plans to invest ₹788 cr. to expand operations in Hyderabad’s Genome Valley

Syngene to invest up to ₹788 cr in Genome Valley, Hyderabad. Expansion to create 1,000 jobs in science over 5 yrs. Inaugurated PROTAC lab & Central Compound Management facility. Ease of doing business & living in Telangana praised by Syngene's non-executive chairperson Kiran Mazumdar Shaw.

The Hindu

Buzzing breakthrough: genetic engineering gives mosquito control an upgrade

Mosquitoes have plagued humans for centuries, transmitting deadly diseases. To combat this, we now have access to the whole genome sequences of multiple mosquito species, allowing us to genetically manipulate them. Gene-drive technology is one such approach, which has been used in outdoor trials in India, Brazil, and Panama, showing…

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